One third of all Danes will get a cancer diagnosis in their lifetime. Cancer is caused by a combination of lifestyle factors, environmental factors and genetics. One important risk factor for cancer is the accumulation of mutations in the DNA.
DNA damage may lead to cancer and therefore it is important to test new chemicals/materials for DNA damaging (genotoxic) potential. We have expertise in several in vitro and in vivo methods to test chemicals/materials for genotoxicity such as the comet assay, the Ames assay and determination of mutation frequency.
We also perform molecular epidemiological studies of the interaction between lifestyle factors and genetic variation in relation to risk of breast-, lung- colon- and prostate cancer.
We are involved in several projects that are related to food and food contact materials and we also have long experience with research related to toxicological effects concerning environmental pollutants.
Collaborations
National Laboratory for Sustainable Energi, Risø DTU, Technical University of Denmark
Department of Systems Biology, Technical University of Denmark
